PC-3 Cell Line

The PC-3 cell line, derived from human prostate adenocarcinoma tissue, is an invaluable tool in cancer research. PC-3 cells serve as an excellent in vitro model to explore the biological mechanisms underlying prostate cancer. PC-3 cells are also extensively used to evaluate the efficacy of potential anti-cancer compounds. By studying how these cancer cells proliferate under different conditions, researchers can gain critical insights to develop novel therapeutic strategies.

At Creative Biolabs, we specialize in delivering high-quality PC-3-based proliferation assays that help researchers advance their cancer studies efficiently and accurately. Leveraging years of expertise and state-of-the-art laboratory technologies, we offer comprehensive services tailored to meet the specific needs of our clients. Whether you are investigating drug efficacy or screening new compounds, our PC-3-based assays provide reliable data to support your research objectives.

PC-3 Cell-based Proliferation Assay

Creative Biolabs is committed to delivering robust data through various methods of PC-3 proliferation assays. Our assay services are rigorously designed to ensure reliability and reproducibility. We employ advanced techniques such as MTT, WST-1, and BrdU incorporation assays to accurately measure cell proliferation rates. We deliver detailed data including dose-response curves and IC50 values, which are crucial for assessing the potency of anti-cancer agents. Researchers can rely on our comprehensive and detailed datasets to make well-informed decisions in their studies.

At Creative Biolabs, our PC-3-based proliferation assay services employ a variety of techniques to evaluate cell growth and drug efficacy. Our methods include:

• MTT/MTS Assay: Measures cellular metabolic activity as an indicator of cell viability, proliferation, and cytotoxicity.
• WST-1 Assay: Offers a colorimetric method for the quantification of cell proliferation and viability.
• BrdU Incorporation Assay: Detects DNA synthesis to quantify cell proliferation.
• Cell Counting: Manual or automated counting methods to assess the number of viable cells.
• Flow cytometry: Assesses cell proliferation by staining PC-3 cells with specific fluorescent markers such as CFSE or proliferation markers such as Ki-67, MCM2, and PCNA.

One-Stop Platform for Diverse Cell Proliferation Assays

As a full-service provider, Creative Biolabs offers an integrated platform for various cell proliferation assays, not limited to PC-3 cells. Our one-stop solution encompasses a wide range of cancer cell lines and assay types to cater to diverse research needs. From initial consultation to data interpretation, our dedicated team of scientists works closely with clients at every step, ensuring seamless project execution. We aim to be a reliable partner in your scientific journey, providing the expertise and support you need to drive impactful discoveries.

Published Data

PC3 cells were treated with 8 concentrations of ZQD for 24 hours and 48 hours. Then cell proliferation was assessed. ZQD inhibited cell proliferation of PC3 cells.

Fig.1 Curve of PC3 cell proliferation after treatment with ZQD.¹

Reference

1. Cao, Hongwen, et al. "Zhoushi Qiling decoction inhibits proliferation of human prostate cancer cells through IL6/STAT3 pathway." Journal of Cancer 14.12 (2023): 2246. Distributed under Open Access license CC BY 4.0, without modification.

For Research Use Only | Not For Clinical Use