Phosphopentomutase-targeted RNA Modification and Metabolomics Analysis Tool
CAT#: ITS-0524-CR293
Cell Type: M2 macrophages
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: HDACs
RNA types: mRNAs
Modification: m1A
RNA editing: C to U
Short Description
This product is a Phosphopentomutase-targeted RNA modification and metabolomics analysis tool based on the m1A (METTL14-YTHDF2-ALKBH5-HDACs-BHQ3) modification and PPP-mediated (PRPF8-Acetyl-CoA-α-KG) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
HDACs
RNA types
mRNAs
Modification
m1A
Label
BHQ3
RNA editing
C to U
Cell Type
M2 macrophages
Oligonucleotide
2'-OMe
RNA Construction
mRNAs-m1A-METTL14-YTHDF2-ALKBH5-HDACs-BHQ3
Substrates
Acetyl-CoA
Cofactors
α-KG
Pathway
PPP
Epigenetic regulator
LSD1 overexpression
Metabolic alteration
Upregulating glycolysis
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
PRPF8
Metabolic Reprogramming
PPP-PRPF8-Acetyl-CoA-α-KG
Target
Phosphopentomutase
Alternative Names
Phosphopentomutase
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.