Probiotic Test Service

Introduction of Probiotic Assessment

Probiotics are live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. The global market for probiotics has grown at a rapid pace, making the precise assessment of product quality and viability a matter of paramount importance. Scientific literature underscores that the simple enumeration of colony-forming units (CFUs) constitutes an incomplete metric of a probiotic's efficacy. This is due to the phenomenon where numerous beneficial bacteria can enter a viable but non-culturable state under specific environmental conditions.

To explore how our services can benefit your project, request a consultation.

Fig 1. Probiotic bacteria exert multiple effects on the intestinal environment. (OA Literature)

Fig.1 Main probiotics mechanisms of action. ¹

What We Can Offer

Probiotic Strain Identification

Utilizing advanced molecular methodologies, including PCR and sequencing, we precisely identify the specific species and strains present within a product. This process validates product authenticity and ensures adherence to regulatory requirements for labeling.

Comprehensive Viability Testing

Our methodologies extend beyond traditional Colony Forming Unit (CFU) assays to encompass the evaluation of both culturable and viable but non-culturable cells. This approach provides a more complete and accurate assessment of a probiotic product's true viability and biological potency.

Stress Tolerance Analysis

This service involves an evaluation of a strain's resilience to common environmental stressors, such as exposure to low pH, bile salts, and elevated temperatures, which are typically encountered during manufacturing, storage, and gastrointestinal transit.

Contaminant Screening

Our services incorporate a rigorous screening protocol designed to detect and identify potential microbial contaminants. This procedure is fundamental to ensuring product purity and safety, thereby safeguarding both the brand's reputation and consumer well-being.

Highlights

Scientific Expertise

Creative Biolabs' team combines cutting-edge technology with deep scientific expertise. Our advanced methods go beyond traditional CFU counts, providing a more accurate assessment of viable cells, including those in a "viable but non-culturable" state.

Advanced Technology

We leverage advanced techniques like flow cytometry to provide real-time results and improved precision in quantifying microorganisms. This ensures we accurately capture the true viability of the microbes in your product, delivering reliable data you can trust.

Holistic Assessment

Our comprehensive approach addresses the limitations of standard methods, providing a more complete picture of your product's quality. We evaluate not only viability but also key stress tolerance characteristics.

Collaborative Partnership

We believe in transparent communication. Our team works with you as a partner from the initial project design to the final report, ensuring you are fully informed throughout the entire process.

To fully understand the Creative Biolabs advantage, we invite you to get a quote today.

Customer Reviews

Optimized Formulation & Survivability
Using Creative Biolabs' probiotic test service in our research has significantly improved our ability to accurately quantify viable probiotic cells. The detailed stress tolerance data were particularly useful in optimizing our formulation for improved survivability in the gut. - R***n K.

Streamlined Quality Control
The strain-specific identification service provided by Creative Biolabs has greatly facilitated our quality control process. We were able to confirm the authenticity of our raw materials with confidence, which has been critical for our product's credibility. - J***y C.

FAQs

What kind of materials do I need to provide for testing?

We can work with a variety of materials, including finished products (powders, capsules, liquids), raw probiotic cultures, and even complex, multi-strain blends. Our team will guide you on the specific requirements during the project consultation to ensure a smooth process.

How long will it take to get my results?

Project timelines vary based on the complexity and scope of the requested services. Generally, a typical project is completed within 2 to 4 weeks. We are committed to providing timely updates and will work with you to meet your project deadlines.

Related Services

Gut Microbiome Model Development and Validation Service

We provide in vitro and in vivo platforms to study the complex interactions between probiotics, host immunity, and disease. This service assists in validating therapeutic effects and understanding the mechanisms of action.

Learn More →

Gut Microbiome Signature Identification

Using multi-omics analysis, we identify specific microbial signatures and biomarkers associated with health conditions. This service is essential for understanding the gut microbiome's role in diagnostics and therapeutic development.

Learn More →

How to Contact Us

Creative Biolabs' probiotic test service provides you with the data and insights you need to confidently bring your product to market and stand out in a competitive industry. For detailed information on our services or to discuss your specific project needs, please do not hesitate to contact us.

Reference

Bermúdez-Humarán, Luis G et al. "Exploring the interaction and impact of probiotic and commensal bacteria on vitamins, minerals and short chain fatty acids metabolism." Microbial cell factories vol. 23,1 172. 12 Jun. 2024. Distributed under an Open Access license CC BY 4.0, without modification. https://doi.org/10.1186/s12934-024-02449-3