RRM2B-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR203
Cell Type: DCs
RNA writers: PCIF1
RNA readers: /
RNA erasers: FTO
Enzymes: HDACs
RNA types: tRNA
Modification: m7G
RNA editing: G to A
Short Description
This product is a RRM2B-targeted RNA modification and metabolomics analysis tool based on the m7G (PCIF1-FTO-HDACs-spacer C9) modification and Mevalonate pathway-mediated (hnRNPs-Succinyl-CoA-ATP) metabolic analysis system.
RNA writers
PCIF1
RNA readers
/
RNA erasers
FTO
Enzymes
HDACs
RNA types
tRNA
Modification
m7G
Label
spacer C9
RNA editing
G to A
Cell Type
DCs
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
tRNA-m7G-PCIF1-FTO-HDACs-spacer C9
Substrates
Succinyl-CoA
Cofactors
ATP
Pathway
Mevalonate pathway
Epigenetic regulator
KMT2D deficiency
Metabolic alteration
Upregulating glycolysis
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Mevalonate pathway-hnRNPs-Succinyl-CoA-ATP
Target
RRM2B
Alternative Names
RRM2B; MTDPS8A; MTDPS8B; P53R2; ribonucleotide reductase regulatory TP53 inducible subunit M2B; RCDFRD
Gene ID
50484(Human)
UniProt ID
Q7LG56(Human)
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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