SigPath™ Phenylalanine Assay Kit

CAT#: ITS-1125-HM42
Product Type: Assay Kit
Species: All Species
Brand: SigPath
Development Stage: Research-Grade Signal Pathway Assay Development
Short Description
Quantifies phenylalanine using a specific dehydrogenase reaction.
Brand
SigPath
Development Stage
Research-Grade Signal Pathway Assay Development
Description
The SigPath™ Phenylalanine Assay Kit offers a rapid, plate-based alternative to HPLC for screening phenylketonuria (PKU) and other amino acid metabolic disorders. This assay is essential for the development of enzyme replacement therapies and dietary interventions for metabolic diseases. Its ability to accurately quantify serum phenylalanine supports pharmacokinetic studies and the monitoring of therapeutic efficacy in clinical research.
Features
Rapid plate-based format replaces HPLC methods; Essential for high-volume metabolic screening of newborn errors.
Process Relevance
Metabolic Disorder Diagnosis
Application Stage
Clinical Research
Applications
Screening for Phenylketonuria (PKU) and metabolic disorders in serum.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Fluorescence Detection (Ex 530 nm / Em 595 nm)
Sample Type
Serum, urine samples
Research Areas
Genetic Metabolic Disorders (PKU)
Size
100 tests
Data Output Type
Quantitative (Concentration)
Assay Time
Results in 30 min
LOD
2 µM
Species
All Species
Storage
Store at −20 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to −20 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
6 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Phenylalanine is an essential aromatic amino acid. The genetic inability to metabolize it leads to Phenylketonuria (PKU) where toxic accumulation causes severe neurological damage if not managed by diet.
For Research Use Only | Not For Clinical Use
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