Short Description
Quantifies phenylalanine using a specific dehydrogenase reaction.
Development Stage
Research-Grade Signal Pathway Assay Development
Description
The SigPath™ Phenylalanine Assay Kit offers a rapid, plate-based alternative to HPLC for screening phenylketonuria (PKU) and other amino acid metabolic disorders. This assay is essential for the development of enzyme replacement therapies and dietary interventions for metabolic diseases. Its ability to accurately quantify serum phenylalanine supports pharmacokinetic studies and the monitoring of therapeutic efficacy in clinical research.
Features
Rapid plate-based format replaces HPLC methods; Essential for high-volume metabolic screening of newborn errors.
Process Relevance
Metabolic Disorder Diagnosis
Application Stage
Clinical Research
Applications
Screening for Phenylketonuria (PKU) and metabolic disorders in serum.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Fluorescence Detection (Ex 530 nm / Em 595 nm)
Sample Type
Serum, urine samples
Research Areas
Genetic Metabolic Disorders (PKU)
Datasheet