1,3BPG-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR93
Cell Type: CD8 T Cells
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: IDH2
RNA types: rRNA
Modification: m1A
RNA editing: A to I
Short Description
This product is a 1,3BPG-targeted RNA modification and metabolomics analysis tool based on the m1A (METTL14-YTHDF2-ALKBH5-IDH2-spacer C18) modification and Mevalonate pathway-mediated (RBFOX2-Acetyl-CoA-α-KG) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
IDH2
RNA types
rRNA
Modification
m1A
Label
spacer C18
RNA editing
A to I
Cell Type
CD8 T Cells
Oligonucleotide
PS, 2'-OMe, 2'-F, GalNAc
RNA Construction
rRNA-m1A-METTL14-YTHDF2-ALKBH5-IDH2-spacer C18
Substrates
Acetyl-CoA
Cofactors
α-KG
Pathway
Mevalonate pathway
Epigenetic regulator
LSD1 overexpression
Metabolic alteration
Upregulating glycolysis
Targeting diseases
Adrenocortical carcinoma
RNA-binding proteins
RBFOX2
Metabolic Reprogramming
Mevalonate pathway-RBFOX2-Acetyl-CoA-α-KG
Target
1,3BPG
Alternative Names
1;3-Bisphosphoglyceric acid (1;3-Bisphosphoglycerate; 1;3BPG
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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