Pyruvate Decarboxylase-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR103
Cell Type: DCs
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: HDACs
RNA types: mRNAs
Modification: m5C
RNA editing: G to A
Short Description
This product is a Pyruvate decarboxylase-targeted RNA modification and metabolomics analysis tool based on the m5C (METTL14-YTHDF2-ALKBH5-HDACs-spacer C9) modification and Mevalonate pathway-mediated (hnRNPs-Succinyl-CoA-ADP) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
HDACs
RNA types
mRNAs
Modification
m5C
Label
spacer C9
RNA editing
G to A
Cell Type
DCs
Oligonucleotide
2'-OMe
RNA Construction
mRNAs-m5C-METTL14-YTHDF2-ALKBH5-HDACs-spacer C9
Substrates
Succinyl-CoA
Cofactors
ADP
Pathway
Mevalonate pathway
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Mevalonate pathway-hnRNPs-Succinyl-CoA-ADP
Target
Pyruvate decarboxylase
Alternative Names
Pyruvate decarboxylase
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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