3-Mercaptopyruvate Sulfurtransferase-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR228
Cell Type: MDSCs
RNA writers: METTL3
RNA readers: YTHDC1
RNA erasers: ALKBH5
Enzymes: ALKBH5
RNA types: mRNAs
Modification: m6Am
RNA editing: A to I
Short Description
This product is a 3-mercaptopyruvate sulfurtransferase-targeted RNA modification and metabolomics analysis tool based on the m6Am (METTL3-YTHDC1-ALKBH5-ALKBH5-spacer C9) modification and Mevalonate pathway-mediated (RBFOX2-SAM-NAD+) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDC1
RNA erasers
ALKBH5
Enzymes
ALKBH5
RNA types
mRNAs
Modification
m6Am
Label
spacer C9
RNA editing
A to I
Cell Type
MDSCs
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
mRNAs-m6Am-METTL3-YTHDC1-ALKBH5-ALKBH5-spacer C9
Substrates
SAM
Cofactors
NAD+
Pathway
Mevalonate pathway
Epigenetic regulator
ACLY overexpression
Metabolic alteration
Increasing the content of acetyl-CoA
Targeting diseases
Adrenocortical carcinoma
RNA-binding proteins
RBFOX2
Metabolic Reprogramming
Mevalonate pathway-RBFOX2-SAM-NAD+
Target
3-mercaptopyruvate sulfurtransferase
Alternative Names
3-mercaptopyruvate sulfurtransferase
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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