Short Description
This product is a mtFASII-targeted RNA modification and metabolomics analysis tool based on the m5C (METTL14-YTHDF2-ALKBH5-ALKBH5-spacer C18) modification and Fatty acid synthesis-mediated (α-synuclein-SAM-ADP) metabolic analysis system.
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
mRNAs-m5C-METTL14-YTHDF2-ALKBH5-ALKBH5-spacer C18
Pathway
Fatty acid synthesis
Epigenetic regulator
SMARCA4 deficiency
Metabolic alteration
Upregulating oxidative phosphorylation
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
α-synuclein
Metabolic Reprogramming
Fatty acid synthesis-α-synuclein-SAM-ADP