mtFASII-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR362
Cell Type: M2 macrophages
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: ALKBH5
RNA types: mRNAs
Modification: m5C
RNA editing: A to I
Short Description
This product is a mtFASII-targeted RNA modification and metabolomics analysis tool based on the m5C (METTL14-YTHDF2-ALKBH5-ALKBH5-spacer C18) modification and Fatty acid synthesis-mediated (α-synuclein-SAM-ADP) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
ALKBH5
RNA types
mRNAs
Modification
m5C
Label
spacer C18
RNA editing
A to I
Cell Type
M2 macrophages
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
mRNAs-m5C-METTL14-YTHDF2-ALKBH5-ALKBH5-spacer C18
Substrates
SAM
Cofactors
ADP
Pathway
Fatty acid synthesis
Epigenetic regulator
SMARCA4 deficiency
Metabolic alteration
Upregulating oxidative phosphorylation
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
α-synuclein
Metabolic Reprogramming
Fatty acid synthesis-α-synuclein-SAM-ADP
Target
mtFASII
Alternative Names
mtFASII
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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