CoA-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR76
Cell Type: M1 macrophages
RNA writers: METTL3
RNA readers: YTHDF1
RNA erasers: FTO
Enzymes: MDH1
RNA types: mRNAs
Modification: m1A
RNA editing: C to U
Short Description
This product is a CoA-targeted RNA modification and metabolomics analysis tool based on the m1A (METTL3-YTHDF1-FTO-MDH1-spacer C9) modification and Mevalonate pathway-mediated (CPEB4-SAM-NAD+) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
MDH1
RNA types
mRNAs
Modification
m1A
Label
spacer C9
RNA editing
C to U
Cell Type
M1 macrophages
Oligonucleotide
2'-OMe (cationic lipoplex)
RNA Construction
mRNAs-m1A-METTL3-YTHDF1-FTO-MDH1-spacer C9
Substrates
SAM
Cofactors
NAD+
Pathway
Mevalonate pathway
Epigenetic regulator
P300/CBP overexpression
Metabolic alteration
Upregulating glycolysis and amino acidsmetabolism
Targeting diseases
Adrenocortical carcinoma
RNA-binding proteins
CPEB4
Metabolic Reprogramming
Mevalonate pathway-CPEB4-SAM-NAD+
Target
CoA
Alternative Names
Coenzyme A; CoASH; CoA
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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