Short Description
This product is a 6-Phosphogluconate-targeted RNA modification and metabolomics analysis tool based on the ac4C (METTL14-YTHDF2-ALKBH5-HDACs-spacer C9) modification and Mevalonate pathway-mediated (α-synuclein-SAM-NAD+) metabolic analysis system.
Oligonucleotide
PS, 2'-OMe, 2'-F, GalNAc
RNA Construction
mRNAs-ac4C-METTL14-YTHDF2-ALKBH5-HDACs-spacer C9
Pathway
Mevalonate pathway
Epigenetic regulator
KDM4C overexpression
Metabolic alteration
Upregulating amino acids metabolism
Targeting diseases
Breast Cancer
RNA-binding proteins
α-synuclein
Metabolic Reprogramming
Mevalonate pathway-α-synuclein-SAM-NAD+
Datasheet