6-Phosphogluconate-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR114
Cell Type: M2 macrophages
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: HDACs
RNA types: mRNAs
Modification: ac4C
RNA editing: A to I
Short Description
This product is a 6-Phosphogluconate-targeted RNA modification and metabolomics analysis tool based on the ac4C (METTL14-YTHDF2-ALKBH5-HDACs-spacer C9) modification and Mevalonate pathway-mediated (α-synuclein-SAM-NAD+) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
HDACs
RNA types
mRNAs
Modification
ac4C
Label
spacer C9
RNA editing
A to I
Cell Type
M2 macrophages
Oligonucleotide
PS, 2'-OMe, 2'-F, GalNAc
RNA Construction
mRNAs-ac4C-METTL14-YTHDF2-ALKBH5-HDACs-spacer C9
Substrates
SAM
Cofactors
NAD+
Pathway
Mevalonate pathway
Epigenetic regulator
KDM4C overexpression
Metabolic alteration
Upregulating amino acids metabolism
Targeting diseases
Breast Cancer
RNA-binding proteins
α-synuclein
Metabolic Reprogramming
Mevalonate pathway-α-synuclein-SAM-NAD+
Target
6-Phosphogluconate
Alternative Names
6-Phosphogluconate
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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