AccuMetab™ Human NADPH-P450 Reductase, Catalytically Active
CAT#: ITS-0426-YL32
Product Type: Recombinant Phase I Accessory Enzyme
Brand: AccuMetab
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Essential human reductase for supporting robust Phase I assays.
Brand
AccuMetab
Development Stage
ADME
ADME Research Domain
Metabolism
Background
NADPH-P450 Reductase (POR) is the obligate electron donor required for the catalytic function of all microsomal cytochrome P450 enzymes. It is an essential reagent utilized by biochemists to reconstitute pure CYP systems and precisely control the electron transfer rates in custom metabolic assays.
Key Features
Obligate electron donor for Phase I reactions; Reconstitution-grade for custom assay building; Precise titration of electron transfer rates; Native human protein lacking background CYPs
Applications
Assay Optimization, Reconstitution Studies
Research Areas
ADME; Assay Development
Species
Human
Expression System
Recombinant enzymes prepared from E. coli membrane preparations.
Physical Form
Liquid
Size
0.5 nmol; 1 nmol; 4 nmol; 10 mg
Storage
-80°C
Storage Comment
When stored at -80°C, our product remains stable and retains full functional activity for up to 10 years.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.