AccuMetab™ Mouse CYP3A11 Enzyme, Catalytically Active

CAT#: ITS-0426-YL50
Product Type: Recombinant Phase I Metabolizing Enzyme
Brand: AccuMetab
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Mouse CYP3A11 for reliable preclinical Phase I ADME profiling.
Brand
AccuMetab
Development Stage
ADME
ADME Research Domain
Metabolism
Background
Serving as the functional murine analog to human CYP3A4, CYP3A11 dictates the first-pass metabolism of numerous drug candidates in mice. It is a critical assay component for determining early in vivo bioavailability and optimizing lead compounds during the discovery phase.
Key Features
Murine equivalent to human CYP3A4; Predicts first-pass clearance in rodent models; Crucial for early-stage discovery scaling; Supplied in controlled, low-reductase formats
Applications
Drug Metabolism Studies, Preclinical Species Comparison
Research Areas
ADME; Preclinical Toxicology
Species
Mouse
Expression System
Recombinant enzymes prepared from E. coli and co-expressed with NADPH CYP-reductase.
Physical Form
Liquid
Size
1 nmol
Storage
-80°C
Storage Comment
When stored at -80°C, our product remains stable and retains full functional activity for up to 10 years.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Our enzyme products are shipped at -80°C.
For Research Use Only | Not For Clinical Use
Online Inquiry