AccuMetab™ Pig CYP2D6 Enzyme, Catalytically Active

CAT#: ITS-0426-YL55
Product Type: Recombinant Phase I Metabolizing Enzyme
Brand: AccuMetab
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Pig CYP2D6 for reliable preclinical Phase I ADME profiling.
Brand
AccuMetab
Development Stage
ADME
ADME Research Domain
Metabolism
Background
This porcine ortholog provides an essential surrogate for evaluating the metabolism of basic and lipophilic therapeutics. Profiling pig CYP2D6 helps clarify species-specific clearance routes and validates the minipig as a robust preclinical model for CNS and cardiovascular drugs.
Key Features
Porcine surrogate for CNS and basic drug clearance; Clarifies minipig species-specific pathways; Pre-coupled with pig NADPH reductase; Supplied in controlled, low-reductase formats
Applications
Drug Metabolism Studies, Preclinical Species Comparison
Research Areas
ADME; Preclinical Toxicology
Species
Pig
Expression System
Recombinant enzymes prepared from E. coli and co-expressed with NADPH CYP-reductase.
Physical Form
Liquid
Size
1 nmol
Storage
-80°C
Storage Comment
When stored at -80°C, our product remains stable and retains full functional activity for up to 10 years.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Our enzyme products are shipped at -80°C.
For Research Use Only | Not For Clinical Use
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