AccuMetab™ Pig CYP2E1 Enzyme, Catalytically Active with Cytochrome b5

CAT#: ITS-0426-YL79
Product Type: Recombinant Phase I Metabolizing Enzyme
Brand: AccuMetab
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Enhanced pig CYP2E1 for high-activity preclinical Phase I profiling.
Brand
AccuMetab
Development Stage
ADME
ADME Research Domain
Metabolism
Background
Adding Cytochrome b5 to porcine CYP2E1 provides a high-activity model for evaluating the rapid generation of hepatotoxic intermediates in swine. It is an essential advanced reagent for translating high-throughput toxicology screens into predictive large-animal in vivo models.
Key Features
Cytochrome b5 supplemented for max catalytic turnover; Drives rapid hepatotoxic intermediate formation in swine; Translates advanced high-throughput tox screening; Highly stable recombinant minipig model
Applications
Enhanced Drug Metabolism Studies, Species Comparison
Research Areas
ADME; Preclinical Toxicology
Species
Pig
Expression System
Recombinant enzymes prepared from E. coli and co-expressed with NADPH CYP-reductase.
Physical Form
Liquid
Size
1 nmol
Storage
-80°C
Storage Comment
When stored at -80°C, our product remains stable and retains full functional activity for up to 10 years.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Our enzyme products are shipped at -80°C.
For Research Use Only | Not For Clinical Use
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