AccuMetab™ Rat CYP1A2 Enzyme, Catalytically Active

CAT#: ITS-0426-YL61
Product Type: Recombinant Phase I Metabolizing Enzyme
Brand: AccuMetab
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Rat CYP1A2 for reliable preclinical Phase I ADME profiling.
Brand
AccuMetab
Development Stage
ADME
ADME Research Domain
Metabolism
Background
Primarily expressed in the rat liver, CYP1A2 metabolizes various environmental toxins and pharmaceutical compounds. It is a standardized in vitro tool used to assess CYP induction potential and predict toxicological outcomes in classical rodent safety testing.
Key Features
Classic rat model for environmental tox; Standardized for in vivo induction prediction; Pre-coupled with rat NADPH reductase; Supplied in controlled, low-reductase formats
Applications
Drug Metabolism Studies, Preclinical Species Comparison
Research Areas
ADME; Preclinical Toxicology
Species
Rat
Expression System
Recombinant enzymes prepared from E. coli and co-expressed with NADPH CYP-reductase.
Physical Form
Liquid
Size
1 nmol
Storage
-80°C
Storage Comment
When stored at -80°C, our product remains stable and retains full functional activity for up to 10 years.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Our enzyme products are shipped at -80°C.
For Research Use Only | Not For Clinical Use
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