P450-Metric™ Cytochrome P450 26B1 (CYP26B1) ELISA Kit

CAT#: ITS-0326-YL15
Product Type: Assay Kit
Species: Mouse
Brand: P450-Metric™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantifies CYP26B1 using a double-antibody sandwich ELISA.
Brand
P450-Metric™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
This exceptionally sensitive double-antibody sandwich ELISA kit provides accurate quantitative analysis of Cytochrome P450 26B1 expression within extrahepatic tissue lysates and homogenates. Featuring broad dynamic range and strict specificity, this research-use-only assay enables investigators to map localized retinoid metabolism effectively. It is a highly valuable analytical tool for assessing target tissue drug exposure and exploring extrahepatic xenobiotic distribution profiles during sophisticated preclinical pharmacokinetic studies.
Features
Engineered for precise quantification, this sandwich ELISA measures CYP26B1 expression reliably, facilitating critical preclinical evaluations of tissue-specific retinoid metabolism and xenobiotic distribution profiles.
Process Relevance
Evaluating CYP26B1 to understand extrahepatic tissue distribution and targeted clearance of retinoid-based drugs.
Application Stage
Preclinical drug discovery, ADME profiling, and pharmacokinetic research
Applications
Quantify specific target enzyme levels in cell lysates, tissue homogenates, and biological fluids using this robust immunoassay.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Sample Type
Serum, plasma, tissue homogenates, cell lysates
Research Areas
ADME; Drug Metabolism; Pharmacokinetics; Toxicology
Size
48 / 96 tests
Data Output Type
Absorbance (OD)
LOD
Mouse: 0.065 ng/mL
Species
Mouse
Storage
Upon receipt, please follow the storage recommendations in the USER MANUAL to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. Do not store at elevated temperatures for extended periods.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Functioning as a critical regulator of retinoic acid levels in extrahepatic tissues, Cytochrome P450 26B1 is integral to cellular differentiation pathways. In toxicological screening, evaluating this enzyme enables the mapping of localized retinoid metabolism and off-target xenobiotic tissue exposure.
For Research Use Only | Not For Clinical Use
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