ACHE-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR235
Cell Type: M1 macrophages
RNA writers: METTL4
RNA readers: /
RNA erasers: FTO
Enzymes: ALKBH5
RNA types: mRNAs
Modification: m6Am
RNA editing: G to A
Short Description
This product is a ACHE-targeted RNA modification and metabolomics analysis tool based on the m6Am (METTL4-FTO-ALKBH5-spacer C9) modification and Gluconeogenesis-mediated (hnRNPs-Succinyl-CoA-ATP) metabolic analysis system.
RNA writers
METTL4
RNA readers
/
RNA erasers
FTO
Enzymes
ALKBH5
RNA types
mRNAs
Modification
m6Am
Label
spacer C9
RNA editing
G to A
Cell Type
M1 macrophages
Oligonucleotide
PO, 2'-OMe, ENA
RNA Construction
mRNAs-m6Am-METTL4-FTO-ALKBH5-spacer C9
Substrates
Succinyl-CoA
Cofactors
ATP
Pathway
Gluconeogenesis
Epigenetic regulator
KDM5A overexpression
Metabolic alteration
Upregulating glycolysis
Targeting diseases
Nasopharyngeal carcinoma
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Gluconeogenesis-hnRNPs-Succinyl-CoA-ATP
Target
ACHE
Alternative Names
ACHE; Acetylcholinesterase
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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