Chloromuconate Cycloisomerase-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR305
Cell Type: M2 macrophages
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: NAMPT
RNA types: tRNA
Modification: ac4C
RNA editing: C to U
Short Description
This product is a Chloromuconate cycloisomerase-targeted RNA modification and metabolomics analysis tool based on the ac4C (METTL14-YTHDF2-ALKBH5-NAMPT-spacer C9) modification and Gluconeogenesis-mediated (hnRNPs-Acetyl-CoA-ADP) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
NAMPT
RNA types
tRNA
Modification
ac4C
Label
spacer C9
RNA editing
C to U
Cell Type
M2 macrophages
Oligonucleotide
PO, 2'-OMe, ENA
RNA Construction
tRNA-ac4C-METTL14-YTHDF2-ALKBH5-NAMPT-spacer C9
Substrates
Acetyl-CoA
Cofactors
ADP
Pathway
Gluconeogenesis
Epigenetic regulator
SMARCA4 deficiency
Metabolic alteration
Upregulating oxidative phosphorylation
Targeting diseases
Nasopharyngeal carcinoma
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Gluconeogenesis-hnRNPs-Acetyl-CoA-ADP
Target
Chloromuconate cycloisomerase
Alternative Names
Muconate cycloisomerase II; Chloromuconate cycloisomerase
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
Online Inquiry