ALAS-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR220
Cell Type: MDSCs
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: HATs
RNA types: mRNAs
Modification: m6A
RNA editing: C to U
Short Description
This product is a ALAS-targeted RNA modification and metabolomics analysis tool based on the m6A (METTL14-YTHDF2-ALKBH5-HATs-TET) modification and Gluconeogenesis-mediated (MBNL-Lactyl-CoA-ATP) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
HATs
RNA types
mRNAs
Modification
m6A
Label
TET
RNA editing
C to U
Cell Type
MDSCs
Oligonucleotide
2'-MOE, GalNAc
RNA Construction
mRNAs-m6A-METTL14-YTHDF2-ALKBH5-HATs-TET
Substrates
Lactyl-CoA
Cofactors
ATP
Pathway
Gluconeogenesis
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
MBNL
Metabolic Reprogramming
Gluconeogenesis-MBNL-Lactyl-CoA-ATP
Target
ALAS
Alternative Names
Aminolevulinic acid synthase (ALA synthase; ALAS
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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