BiliTrack™ Mouse Glutathione Hydrolase 1 Proenzyme (GGT1) ELISA Kit

CAT#: ITS-0326-WB128
Product Type: ELISA Kit
Species: Mouse
Target: Mouse gamma-glutamyltransferase 1 (GGT1)
Brand: BiliTrack™
Development Stage: ADME
ADME Research Domain: Excretion
Short Description
Quantitatively detects mouse GGT1 protein levels in biological samples using a sensitive ELISA assay.
Brand
BiliTrack™
Development Stage
ADME
ADME Research Domain
Excretion
Description
BiliTrack™ Mouse Glutathione Hydrolase 1 Proenzyme (GGT1) ELISA Kit is a sensitive sandwich ELISA developed for the quantitative detection of GGT1 in mouse biological samples. The assay enables accurate measurement of GGT1 levels in serum, plasma, tissue lysates, and cultured cells, supporting studies of glutathione metabolism, oxidative stress regulation, and liver-related biochemical processes.
Features
Highly sensitive sandwich ELISA format enables reliable quantification of mouse GGT1 across a broad dynamic range in diverse biological samples.
Optimized antibody pair specifically recognizes mouse GGT1 while minimizing background interference and cross-reactivity with related gamma-glutamyltransferase family proteins.
Pre-coated microplate and validated reagents streamline experimental workflows while ensuring consistent and reproducible assay performance.
Compatible with multiple mouse sample matrices including serum, plasma, tissue extracts, and cultured cell lysates.
Process Relevance
Measures GGT1 expression to evaluate glutathione metabolism and oxidative stress-related biochemical alterations.
Application Stage
Basic research, toxicology studies, liver disease models, and metabolic pathway analysis.
Applications
Quantitative measurement of mouse GGT1 in serum, plasma, tissue lysates, or cultured cells for oxidative stress studies, metabolic enzyme analysis, toxicology evaluation, ADME profiling studies, and biomarker research.
Target
Mouse gamma-glutamyltransferase 1 (GGT1)
Detection Method
Colorimetric
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Assay Measures
Quantitative
Research Areas
Liver biology, oxidative stress research, glutathione metabolism, toxicology, pharmacokinetics (ADME), metabolic enzyme studies, biomarker discovery, etc.
Size
96 tests
Data Output Type
Quantitative protein concentration measurement using absorbance-based endpoint ELISA detection.
Assay Range
0.16 ng/ml - 10 ng/ml
LOD
0.1 ng/ml
Species
Mouse
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Gamma-glutamyltransferase 1 (GGT1) is a membrane-associated enzyme responsible for catalyzing the first step of extracellular glutathione degradation. This process contributes to amino acid transport and cellular antioxidant defense. Dysregulated GGT1 expression has been associated with oxidative stress, liver injury, and metabolic disorders.
Pathways
GGT1 plays a central role in the gamma-glutamyl cycle, which regulates glutathione turnover and amino acid transport. By hydrolyzing extracellular glutathione, GGT1 supports intracellular cysteine availability for glutathione resynthesis. This pathway links antioxidant defense mechanisms with metabolic and detoxification processes.
For Research Use Only | Not For Clinical Use
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