Diacetyl Reductase-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR152
Cell Type: M2 macrophages
RNA writers: TRMT61B
RNA readers: YTHDF1/2/3
RNA erasers: ALKBH1
Enzymes: HDACs
RNA types: tRNA
Modification: m5C
RNA editing: T to C
Short Description
This product is a Diacetyl reductase-targeted RNA modification and metabolomics analysis tool based on the m5C (TRMT61B-YTHDF1/2/3-ALKBH1-HDACs-DBCO) modification and TCA cycle-mediated (RBFOX1-Lactyl-CoA-ADP) metabolic analysis system.
RNA writers
TRMT61B
RNA readers
YTHDF1/2/3
RNA erasers
ALKBH1
Enzymes
HDACs
RNA types
tRNA
Modification
m5C
Label
DBCO
RNA editing
T to C
Cell Type
M2 macrophages
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
tRNA-m5C-TRMT61B-YTHDF1/2/3-ALKBH1-HDACs-DBCO
Substrates
Lactyl-CoA
Cofactors
ADP
Pathway
TCA cycle
Epigenetic regulator
G9A overexpression
Metabolic alteration
Upregulating serine-glycine biosyntheticpathway
Targeting diseases
Lung Cancer
RNA-binding proteins
RBFOX1
Metabolic Reprogramming
TCA cycle-RBFOX1-Lactyl-CoA-ADP
Target
Diacetyl reductase
Alternative Names
Diacetyl reductase
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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