PP1-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR137
Cell Type: M2 macrophages
RNA writers: METTL3
RNA readers: YTHDF1
RNA erasers: FTO
Enzymes: HDACs
RNA types: mRNAs
Modification: ac4C
RNA editing: C to U
Short Description
This product is a PP1-targeted RNA modification and metabolomics analysis tool based on the ac4C (METTL3-YTHDF1-FTO-HDACs-DBCO) modification and Fatty acid metabolism-mediated (α-synuclein-SAM-α-KG) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
HDACs
RNA types
mRNAs
Modification
ac4C
Label
DBCO
RNA editing
C to U
Cell Type
M2 macrophages
Oligonucleotide
2'-OMe (cationic lipoplex)
RNA Construction
mRNAs-ac4C-METTL3-YTHDF1-FTO-HDACs-DBCO
Substrates
SAM
Cofactors
α-KG
Pathway
Fatty acid metabolism
Epigenetic regulator
SIRT6 deficiency
Metabolic alteration
Upregulating glycolysis
Targeting diseases
Hepatocellular Carcinoma
RNA-binding proteins
α-synuclein
Metabolic Reprogramming
Fatty acid metabolism-α-synuclein-SAM-α-KG
Target
PP1
Alternative Names
Protein phosphatase 1; PP1
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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