PharmaOnco™ HER2/Neu-Specific T cells

Creative Biolabs offers HER2/Neu-Specific T cells for immunity reaserch.

HER2/Neu-specific T cells are a type of immune cell that has been modified to target and attack cancer cells that express the HER2/Neu protein. This protein is commonly found on the surface of breast cancer cells, making it a promising target for immunotherapy. These T cells are engineered to express a chimeric antigen receptor (CAR) that specifically recognizes the HER2/Neu protein, allowing them to selectively kill cancer cells while sparing healthy cells.

HER2/Neu-specific T cells are a type of immune cell that has been genetically engineered to target and kill cancer cells expressing the HER2/Neu protein. HER2/Neu is a cell surface receptor that is overexpressed in a variety of cancer types, including breast cancer and ovarian cancer. By targeting HER2/Neu-expressing cancer cells, HER2/Neu-specific T cells can help to destroy the tumor and potentially improve patient outcomes. These T cells are created by taking T cells from a patient's blood and then genetically modifying them to express a chimeric antigen receptor (CAR) that is specific for the HER2/Neu protein. Once infused back into the patient, these engineered T cells can recognize and attack cancer cells that express HER2/Neu, leading to tumor regression and potentially long-term remission.

Human

T cell population

We recommend RPMI-1640 with 10% FBS media for our functional analysis, but that depends on the media used by customers for co-culturing experiments.

High quality;
High viability;
Widely applications.

With proper stimulation, they will survive for about 4-5 days.

HER2/Neu (369-377)

Male

48

Normal

2:01:00

7:02:00

3:03:00

A+

Caucasian

Acid-citrate-dextrose solution A (ACDA)

Contact us for donor specifications (Age,Gender,BMI category, smoking status, ethnicity, etc.).

Contains Cryopreservation Medium

>80%

>80%

Negative

Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.

We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.

Immunotherapy Discovery and Development

Cultures are screened for the presence of bacteries, yeast, fungi and mycoplasma (DNA amplification). Growth media are also certified based on U.S. Public Health Service Guidelines.

Frozen cells should be stored in a liquid nitrogen tank (-150°C~-195°C).

Frozen cells should be thawed according to handling procedure or stored in a liquid nitrogen tank.

Avoid multiple freeze/thaw cycles.

1 x 10e6 cells/vial

Frozen

Certain products are only available in select territories. Please contact us for more information.