PharmaOnco™ CMV-Specific CD4+ T cells

CAT#: ITS-0423-LX1
Product Type: OncoImmune Cells
Cell Type: CD4+ T cell
Species: Human
Short Description
Creative Biolabs offers CMV-Specific CD4+ T cells for immunity reaserch.
Description
CMV-specific CD4+ T cells are a subset of T cells that are specifically targeted against cytomegalovirus (CMV), a common virus in the herpes family. These cells play a crucial role in the immune response against CMV infection, as they help to coordinate and regulate the activities of other immune cells such as CD8+ T cells, B cells, and macrophages.
Background
CMV-specific CD4+ T cells are a subset of T cells that are specific for cytomegalovirus (CMV), a common viral infection in humans. These T cells play a crucial role in the immune response against CMV infection by recognizing and targeting infected cells for destruction. One of the key functions of CMV-specific CD4+ T cells is to help activate other immune cells, such as CD8+ T cells and B cells, to mount an effective immune response against the virus. They do this by releasing cytokines and other signaling molecules that stimulate the activation and proliferation of these other immune cells.
Species
Human
Cell Type
CD4+ T cell
Culture medium
We recommend RPMI-1640 with 10% FBS media for our functional analysis, but that depends on the media used by customers for co-culturing experiments.
Features
High quality;
High viability;
Widely applications.
Survive Time
With proper stimulation, they will survive for about 4-5 days.
Antigen
CMV
Gender
Female
Donor Age
31
Donor Health
Normal
HLA-A
2:01:00
HLA-B
18:01:00
HLA-C
3:04:00
Blood Type
A-
Ethnicity
Caucasian
Anticoagulant
Acid-citrate-dextrose solution A (ACDA)
Additional Donor Information
Contact us for donor specifications (Age,Gender,BMI category, smoking status, ethnicity, etc.).
Formulation
Contains Cryopreservation Medium
Cell Purity
>80%
Cell Viability
>80%
Mycoplasma Testing
Negative
Sterility Testing
Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.
Genetic Stability Testing
We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.
Application
Immunotherapy Discovery and Development
Quality Control
Cultures are screened for the presence of bacteries, yeast, fungi and mycoplasma (DNA amplification). Growth media are also certified based on U.S. Public Health Service Guidelines.
Storage
Frozen cells should be stored in a liquid nitrogen tank (-150°C~-190°C).
Handling Notes
Frozen cells should be thawed according to handling procedure or stored in a liquid nitrogen tank.
Warnings
Avoid multiple freeze/thaw cycles.
Size
1 x 10e6 cells/vial
Status
Frozen
Note
Certain products are only available in select territories. Please contact us for more information.
For Research Use Only | Not For Clinical Use
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