Creative Biolabs offers Human CD8+//CD45RA+ Naïve T Cells for immunity reaserch.
Description
CD8+//CD45RA+ naïve T cells, also known as naïve cytotoxic T cells, are a subset of T cells in the immune system that have not been exposed to antigens and are in a resting state. These cells express the glycoprotein CD8 on their cell surface, which allows them to recognize and bind to antigens presented by major histocompatibility complex (MHC) class I molecules on infected or abnormal cells. Naïve CD8+//CD45RA+ T cells play a critical role in the adaptive immune response by providing a pool of antigen-specific cytotoxic T cells that can respond rapidly to pathogens and provide long-lasting immunity.
Background
CD8+ cells, also known as cytotoxic T cells, are a type of white blood cell that play a critical role in the immune system's response to infections and cancer. These cells are responsible for recognizing and destroying infected or abnormal cells in the body. CD8+ cells are able to recognize specific antigens on the surface of target cells, leading to the release of toxic molecules that induce cell death. This process helps to eliminate infected cells and prevent the spread of pathogens. In addition to their role in fighting infections, CD8+ cells also play a key role in the immune response to cancer. By targeting and destroying cancerous cells, these cells help to prevent the development and progression of tumors.
Species
Human
Cell Type
CD8+CD45RA+, CD8+, T cells
Source
Peripheral Blood
Features
High quality; High viability; Widely applications.
Donor Health
Normal
Anticoagulant
Acid-citrate-dextrose solution A (ACDA)
Additional Donor Information
Contact us for donor specifications (Age,Gender,BMI category, smoking status, ethnicity, etc.).
Formulation
Contains Cryopreservation Medium
Cell Purity
> 85% CD8+CD45RA+CCR7+CD45RO-CD56-CD57- by flow cytometry
Mycoplasma Testing
Negative
Sterility Testing
Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.
Genetic Stability Testing
We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.
Application
Immunotherapy Discovery and Development
Research Use Only
Our products are for research use only, not for diagnostic or therapeutic use.
Quality Control
Donors are screened for HIV-1, HIV-2, hepatitis B, and hepatitis C.
Storage
Store at -135°C or colder for 12 months from date of receipt.
Handling Notes
When handling biohazardous materials such as human cells, safe laboratory procedures should be followed and protective clothing should be worn.
Warnings
Creative Biolabs cannot guarantee the biological function or any other properties associated with performance of this product in a researcher's individual assay or culture systems.
Size
1 x 10e6 cells/vial
Status
Frozen
Note
Certain products are only available in select territories. Please contact us for more information.