PharmaOnco™ Human Mature Dendritic Cells, Peripheral Blood

Creative Biolabs offers Human Mature Dendritic Cells, Peripheral Blood for drug discovery and toxicity testing, iImmunology.

Creative Biolabs provides a reliable ethically sourced, ready-to-use Human Mature Dendritic Cells from Peripheral Blood. This product allows for study in numerous immunity research areas.

Mature dendritic cells are immune cells that have undergone a process of maturation, during which they have acquired the ability to effectively present antigens to T cells and initiate an adaptive immune response. This process involves the upregulation of co-stimulatory molecules and antigen-presenting receptors, as well as the secretion of cytokines that promote T cell activation and differentiation. Mature dendritic cells are typically found in peripheral tissues, where they constantly sample their environment for foreign antigens. Once they encounter an antigen, they internalize it and process it into smaller peptides that can be displayed on their cell surface in complex with major histocompatibility complex molecules. This allows them to interact with T cells and initiate an immune response against the specific antigen. Mature dendritic cells play a critical role in the activation and regulation of both the innate and adaptive immune responses. They are considered to be the most potent antigen-presenting cells in the body and are essential for the initiation of immune responses against pathogens and tumor cells.

Human

B Cells

Peripheral blood

PRMI1640

High quality;
High viability;
Widely applications.

Normal

Contact us for donor specifications (Age,Gender,BMI category, smoking status, ethnicity, etc.).

Contains Cryopreservation Medium

> 80%

Negative

Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.

We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.

All cells were collected under Institutional Review Board (IRB)-approved consent forms and protocols.

Immunotherapy Discovery and Development

Donors are negative for HIV-1, HIV-2, hepatitis B, and hepatitis C.

Stored at < -120°C once they are received.

Frozen cells should be thawed according to handling procedure or stored in a liquid nitrogen tank.

Avoid multiple freeze/thaw cycles.

1 x 10e6 cells/vial

Frozen

Certain products are only available in select territories. Please contact us for more information.