Creative Biolabs offers Influenza (M1)-Specific T cells for immunity reaserch.
Description
Influenza (M1)-specific T cells are a type of immune cells that are specifically activated to recognize and target the M1 protein of the influenza virus. These T cells play a key role in the immune response to influenza infection by recognizing infected cells displaying the M1 protein on their surface and killing them to prevent the spread of the virus.
Background
Influenza (M1)-specific T cells are a subset of T cells that specifically recognize and target a protein from the influenza virus called M1. These T cells play a critical role in the immune response to influenza infection by recognizing infected cells displaying M1 protein on their surfaces and initiating the destruction of these cells. Influenza-specific T cells can be either CD4+ T cells (helper T cells) or CD8+ T cells (cytotoxic T cells). CD4+ T cells help coordinate the immune response by activating other immune cells, while CD8+ T cells directly kill infected cells. During an influenza infection, these specific T cells undergo activation and proliferation to quickly target and eliminate virus-infected cells. This helps to limit the spread of the virus and reduce the severity of the infection.
Species
Human
Cell Type
T cell population
Culture medium
We recommend RPMI-1640 with 10% FBS media for our functional analysis, but that depends on the media used by customers for co-culturing experiments.
Features
High quality; High viability; Widely applications.
Survive Time
With proper stimulation, they will survive for about 4-5 days.
Antigen
Influenza (M1) (GILGFVFTL)
HLA Restricted
HLA-A*0201
Gender
Female
Donor Age
31
Donor Health
Normal
HLA-A
2:01:02
HLA-B
18:01:00
HLA-C
3:04:00
Blood Type
A-
Ethnicity
Caucasian
Anticoagulant
Acid-citrate-dextrose solution A (ACDA)
Additional Donor Information
Contact us for donor specifications (Age,Gender,BMI category, smoking status, ethnicity, etc.).
Formulation
Contains Cryopreservation Medium
Cell Purity
>80%
Cell Viability
>80%
Mycoplasma Testing
Negative
Sterility Testing
Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.
Genetic Stability Testing
We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.
Application
Immunotherapy Discovery and Development
Quality Control
Cultures are screened for the presence of bacteries, yeast, fungi and mycoplasma (DNA amplification). Growth media are also certified based on U.S. Public Health Service Guidelines.
Storage
Frozen cells should be stored in a liquid nitrogen tank (-150°C~-200°C).
Handling Notes
Frozen cells should be thawed according to handling procedure or stored in a liquid nitrogen tank.
Warnings
Avoid multiple freeze/thaw cycles.
Size
1 x 10e6 cells/vial
Status
Frozen
Note
Certain products are only available in select territories. Please contact us for more information.