PharmaOnco™ NFAT Reporter (Luc) - Jurkat Cell Line (Human)

The NFAT Reporter - Jurkat Cell Line contains a firefly luciferase gene under the control of the; NFAT response element stably integrated into Jurkat cells. This cell line has been validated for; response to thapsigargin, ionomycin, and phorbol 12-myristate 13-acetate (PMA). It is useful as; a control cell line for other NFAT reporter cell lines expressing various immune checkpoint; receptors.

Monitor intracellular calcium levels. Screen for activators or inhibitors of PKC/ Ca2+ pathway. Screen for agonists or antagonists of T cell receptors. Control for immune checkpoint NFAT reporter cell lines.

Human

JURKAT

Nuclear factor of activated T cells; T cell

Lymphoid Tissue

2 vials

-80C (dry ice)

Immediately upon receipt, store vials in liquid nitrogen.