lmmune Effector Cell Modulator Development Services for Cancer Immunotherapy

Background

Immunomodulatory inhibitors mainly control the activity of other elements of the immune system to release new or enhance existing immune responses to cancer. Immunomodulatory inhibitors are mainly divided into antagonists and agonists, antagonists mainly work by blocking pathways that inhibit immune cells, such as immune checkpoint inhibitors. Agonists work primarily by stimulating pathways that activate immune cells, such as interleukins (ILs).

Fig.1 Some immune effector cell signaling in immune system networks.¹

Immune Effector Cell Modulator Development Services

Creative Biolabs has conducted in-depth development, optimization, and validation of immune effector cell modulators. We are committed to providing immuno-oncology antagonist and agonist development services that you can choose the best fit for your research project.

Antagonist Development Service for Cancer Immunotherapy
Creative Biolabs focuses on the development of tumor immunomodulators, based on years of experience in tumor immunotherapy development and advanced detection technology platforms, we can provide you with the design of tumor immunosuppressants and the detection of related markers, such as PD-L1 expression level, MMR expression status, MSI, TMB, etc. At the same time, we also provide platform services such as immune cell culture, functional identification, tumor immune microenvironment, and PDX animal models.
Agonist Development Service for Cancer Immunotherapy
Creative Biolabs is committed to better tumor immunotherapy, providing appropriate in vitro/vivo testing services for a variety of agonist targets. We assist you in the development of agonists throughout the process and organize experimental procedures and parameters into a complete protocol for your customers' use, which can help you save development cycles. Our cancer immunotherapy agonist development service platform includes co-stimulatory agonist development and glucopyranosyl lipid A (GLA) system TRL4 agonist development, among others.

Immuno-oncology Related Antagonist / Agonists

Antagonist

Fig.2 Antagonist. (Creative Biolabs Original)

Agonists

Fig.2 Agonists. (Creative Biolabs Original)

Assay We Can Provide

Immune effector cell modulator design
Preparation and characterization of Immune effector cell modulator
In vitro pharmacodynamic evaluation test
In vivo pharmacokinetic assessment

Our Capabilities

Provides different technical means for molecular design and optimization of immune effector cell modulators.
Provides a variety of stable and reliable drugs for the efficacy evaluation of immune effector cell modulators for different targets and pathways.
Offers a variety of effective animal models to test the effectiveness of immune effector cell modulators.
Before the project, a detailed and comprehensive plan is provided. At the end of the project, complete and reliable data results are provided.

You can trust Creative Biolabs to provide comprehensive analytical solutions for immune effector cell modulator researchers. If you are interested or still have questions, you can contact us directly. We operate around the clock and respond within a short period.

Reference

Gangemi, Silvia.; et al. "Occupational and environmental exposure to pesticides and cytokine pathways in chronic diseases (Review)." International journal of molecular medicine. 38,4 (2016): 1012-20.

For Research Use Only | Not For Clinical Use