MetaVital™ Mouse Glutathione S-transferase Mu 5 (GSTM5) ELISA Kit

CAT#: ITS-0326-WB53
Product Type: ELISA Kit
Species: Mouse
Target: Mouse Glutathione S-transferase Mu 5 (GSTM5) protein
Brand: MetaVital™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantitatively measures Mouse GSTM5 levels in tissues, cell lysates, and biological fluids with high specificity.
Brand
MetaVital™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
MetaVital™ Mouse Glutathione S-transferase Mu 5 (GSTM5) ELISA Kit offers a robust in vitro solution for precise quantification of GSTM5 in tissue homogenates, cell lysates, and various biological fluids. This kit enables researchers to investigate GSTM5-related detoxification pathways with reliable sensitivity and reproducibility in preclinical studies.
Features
Highly specific detection of native Mouse GSTM5 with minimal cross-reactivity across GST isoforms, ensuring accurate measurements in complex samples.
Broad quantitative range from 0.156 ng/mL to 10 ng/mL, allowing detection of both low and elevated GSTM5 concentrations.
Colorimetric, plate-based ELISA format optimized for tissue homogenates, cell lysates, and other biological fluids with straightforward workflow.
Lyophilized standards and reagents provide long-term stability, maintaining performance within 5% activity loss under proper storage.
Process Relevance
Enables precise GSTM5 monitoring to support oxidative stress, detoxification, and metabolic pathway investigations.
Application Stage
Drug discovery, mechanistic research, and in vitro preclinical biomarker studies.
Applications
Suitable for quantitative ELISA assays using tissue homogenates, cell lysates, or other biological fluids; supports pathway analysis, pharmacology studies, ADME profiling studies, and biomarker discovery.
Target
Mouse Glutathione S-transferase Mu 5 (GSTM5) protein
Detection Method
Colorimetric
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Assay Measures
Quantitative
Research Areas
Toxicology, pharmacokinetics (ADME), oxidative stress research, pharmacokinetics, metabolic enzyme regulation, preclinical disease modeling, etc.
Size
96 tests
Data Output Type
Quantitative colorimetric measurement of GSTM5 concentrations (endpoint assay).
Assay Range
0.156 ng/ml - 10 ng/ml
Species
Mouse
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
GSTM5 is a key detoxification enzyme within the GST mu family, catalyzing conjugation of electrophilic compounds to glutathione. Its expression reflects cellular defense mechanisms against oxidative stress and xenobiotic damage, making it an important biomarker for metabolic and toxicological studies.
Pathways
GSTM5 participates in glutathione-mediated detoxification pathways, conjugating reactive metabolites to reduce cytotoxicity. It functions downstream of oxidative stress signaling and influences xenobiotic metabolism, supporting cellular homeostasis.
For Research Use Only | Not For Clinical Use
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