MetaVital™ Mouse Monoamine Oxidase B (MAOB) ELISA Kit

CAT#: ITS-0326-WB64
Product Type: ELISA Kit
Species: Mouse
Target: Mouse Monoamine Oxidase B (MAOB)
Brand: MetaVital™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantitatively measures MAOB concentrations in mouse tissue, cells, and biological fluids with high specificity.
Brand
MetaVital™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
The MetaVital™ Mouse MAOB ELISA Kit offers a sensitive, reliable in vitro assay for quantifying Monoamine Oxidase B levels in tissue homogenates, cell lysates, and other biological fluids, enabling precise enzyme activity profiling across preclinical models.
Features
High sensitivity detection with a 9.38 pg/mL lower limit, supporting accurate quantification in low-abundance samples.
Sandwich ELISA format ensures exceptional specificity by dual recognition of MAOB epitopes in complex matrices.
Complete kit includes pre-coated 96-well plates, biotin- and HRP-conjugated reagents, and TMB substrate for efficient workflow.
Stable lyophilized standards and robust storage conditions maintain activity loss below 5% throughout the shelf life.
Process Relevance
Enables precise monitoring of MAOB activity to support enzymatic profiling and neurochemical pathway studies in preclinical research.
Application Stage
Preclinical research, biomarker validation, and in vitro enzymatic activity assessment.
Applications
Suitable for quantitative ELISA analysis in mouse tissue homogenates, cell lysates, cerebrospinal fluid, serum, or plasma, facilitating neurodegenerative and ADME profiling studies.
Target
Mouse Monoamine Oxidase B (MAOB)
Detection Method
Colorimetric
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Assay Measures
Quantitative
Research Areas
Neuroscience, neurodegenerative disease research, pharmacokinetics (ADME), enzymology, pharmacology, biomarker discovery, oxidative stress studies, preclinical translational research, etc.
Size
96 tests
Data Output Type
Quantitative enzyme concentration measurement using colorimetric sandwich ELISA readout.
Assay Range
15.6 pg/ml - 1000 pg/ml
LOD
9.38 pg/ml
Species
Mouse
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
MAOB is a mitochondrial enzyme catalyzing the oxidative deamination of dopamine and other monoamines, influencing neurochemical balance. Dysregulation is linked to Parkinson's disease, aging, and oxidative stress, making it a vital preclinical biomarker.
Pathways
MAOB regulates the catabolism of dopamine and phenylethylamine, producing hydrogen peroxide as a byproduct. Its activity impacts oxidative stress pathways and interacts with mitochondrial metabolism, affecting neuronal survival and neurotransmitter homeostasis.
For Research Use Only | Not For Clinical Use
Online Inquiry