MetaVital™ Rat Glutathione S-Transferase P (GSTP1) ELISA Kit

CAT#: ITS-0326-WB56
Product Type: ELISA Kit
Species: Rat
Target: Rat Glutathione S-Transferase P (GSTP1) protein
Brand: MetaVital™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantitatively measures Rat GSTP1 protein levels in tissues, cells, and biological fluids.
Brand
MetaVital™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
MetaVital™ Rat Glutathione S-Transferase P (GSTP1) ELISA Kit provides a reliable in vitro platform for detecting and quantifying GSTP1 concentrations in tissue homogenates, cell lysates, and biological fluids with high sensitivity and reproducibility.
Features
Employs sandwich ELISA format for precise detection, minimizing cross-reactivity and ensuring accurate quantification of GSTP1 in rat samples.
High sensitivity allows detection down to 0.1 ng/mL, enabling measurement in low-abundance biological samples.
Kit includes lyophilized standards, HRP-conjugated reagents, and pre-coated 96-well plates for convenient, ready-to-use workflow.
Validated for tissue homogenates, cell lysates, and various biological fluids, ensuring broad experimental applicability across research contexts.
Process Relevance
Supports accurate GSTP1 monitoring to optimize enzymatic studies and assess cellular detoxification capacity.
Application Stage
Drug discovery, toxicology studies, and in-process molecular biomarker evaluation.
Applications
Suitable for sandwich ELISA assays of GSTP1, analyzing tissue homogenates, cell lysates, and biological fluids for downstream ADME profiling studies and toxicological research.
Target
Rat Glutathione S-Transferase P (GSTP1) protein
Detection Method
Colorimetric
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Assay Measures
Quantitative
Research Areas
Enzymology, pharmacokinetics (ADME), metabolic pathway analysis, tumor immunology, hepatology, cancer biology, etc.
Size
96 tests
Data Output Type
Quantitative protein concentration measurement using colorimetric detection (endpoint).
Assay Range
0.16 ng/ml - 10 ng/ml
LOD
0.1 ng/ml
Species
Rat
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
GSTP1 is a detoxifying enzyme that catalyzes glutathione conjugation to electrophilic compounds, protecting cells from oxidative stress and xenobiotic toxicity. Its expression correlates with cancer susceptibility and drug resistance, making it a valuable biomarker for toxicology and oncology studies.
Pathways
GSTP1 participates in cellular detoxification and antioxidant defense pathways, modulating glutathione metabolism. It interacts upstream with reactive oxygen species and downstream with conjugated metabolite elimination, influencing oxidative stress responses and drug metabolism.
For Research Use Only | Not For Clinical Use
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