P450-Metric™ Cytochrome P450 4F2 (CYP4F2) ELISA Kit

CAT#: ITS-0326-YL21
Product Type: Assay Kit
Species: Human
Brand: P450-Metric™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantifies CYP4F2 using a double-antibody sandwich ELISA.
Brand
P450-Metric™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
This scientifically optimized double-antibody sandwich ELISA kit is expressly designed for the reliable quantitative analysis of Cytochrome P450 4F2 within selected biological matrices. Highlighting outstanding analytical sensitivity, this research-use-only assay empowers scientists to meticulously examine specialized endogenous eicosanoid metabolism. It forms a critical analytical foundation for evaluating the metabolic stability of lipid-derived therapeutics and assessing unique xenobiotic clearance mechanisms in advanced preclinical ADME investigations.
Features
Engineered for robust performance, this sandwich ELISA accurately measures CYP4F2, allowing researchers to deeply investigate specialized eicosanoid metabolism and targeted xenobiotic clearance in preclinical models.
Process Relevance
Measuring CYP4F2 to evaluate specific phase I DDI risks related to the Vitamin K pathway.
Application Stage
Preclinical drug discovery, ADME profiling, and pharmacokinetic research
Applications
This specific sandwich ELISA quantifies target concentrations across tissue homogenates, cell culture supernates, and complex biological matrices.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Sample Type
Serum, plasma, tissue homogenates, cell lysates
Research Areas
ADME; Drug Metabolism; Pharmacokinetics; Toxicology
Size
48 / 96 tests
Data Output Type
Absorbance (OD)
LOD
Human: 0.55 ng/mL
Species
Human
Storage
Upon receipt, please follow the storage recommendations in the USER MANUAL to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. Do not store at elevated temperatures for extended periods.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Cytochrome P450 4F2 is the primary enzyme driving the omega-hydroxylation and degradation of leukotrienes and various arachidonic acid derivatives. Quantifying its activity is crucial for profiling the metabolic stability of lipid-derived therapeutics and exploring xenobiotic modulations of inflammatory pathways.
For Research Use Only | Not For Clinical Use
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