ModifiSite™ Acetylcholinesterase Assay Kit

CAT#: ITS-1125-HM64
Product Type: Assay Kit
Species: All Species
Brand: ModifiSite
Development Stage: Research-Grade Protein & Enzyme Assay Development
Short Description
Determines AChE activity based on thiocholine production.
Brand
ModifiSite
Development Stage
Research-Grade Protein & Enzyme Assay Development
Description
The ModifiSite™ Acetylcholinesterase Assay Kit is a standard tool for screening AChE inhibitors, which are the primary therapeutic class for Alzheimer's disease management. This colorimetric assay validates compounds that enhance cholinergic transmission, supporting neuropharmacology research. It is also used in toxicology to detect exposure to organophosphate pesticides and nerve agents.
Features
Colorimetric method based on Ellman's reagent; Standard tool for screening Alzheimer's disease therapeutics.
Process Relevance
Neurotoxicity & Alzheimer's Screening
Application Stage
Hit-to-Lead Screening
Applications
Neurotoxicity testing and Alzheimer's disease research.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 412 nm
Sample Type
Blood, serum, plasma samples
Research Areas
Neuroscience; Toxicology
Size
100 tests
Data Output Type
Kinetic (Enzyme Activity)
Assay Time
Results in 10 min
LOD
10 U/L
Species
All Species
Storage
Store at room temperature upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Expiry Date
6 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped at room temperature under controlled conditions.
Background
Acetylcholinesterase rapidly breaks down acetylcholine to terminate synaptic transmission. Inhibition of this enzyme is the mechanism of action for nerve agents and therapeutics for Alzheimer's disease.
For Research Use Only | Not For Clinical Use
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