Short Description
This product is a OGDC-targeted RNA modification and metabolomics analysis tool based on the m1A (METTL14-YTHDF2-ALKBH5-ACL-spacer C18) modification and Fatty acid synthesis-mediated (RBFOX3-Acetyl-CoA-α-KG) metabolic analysis system.
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
mRNAs-m1A-METTL14-YTHDF2-ALKBH5-ACL-spacer C18
Pathway
Fatty acid synthesis
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
RBFOX3
Metabolic Reprogramming
Fatty acid synthesis-RBFOX3-Acetyl-CoA-α-KG
Datasheet