OGDC-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR349
Cell Type: M1 macrophages
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: ACL
RNA types: mRNAs
Modification: m1A
RNA editing: C to U
Short Description
This product is a OGDC-targeted RNA modification and metabolomics analysis tool based on the m1A (METTL14-YTHDF2-ALKBH5-ACL-spacer C18) modification and Fatty acid synthesis-mediated (RBFOX3-Acetyl-CoA-α-KG) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
ACL
RNA types
mRNAs
Modification
m1A
Label
spacer C18
RNA editing
C to U
Cell Type
M1 macrophages
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
mRNAs-m1A-METTL14-YTHDF2-ALKBH5-ACL-spacer C18
Substrates
Acetyl-CoA
Cofactors
α-KG
Pathway
Fatty acid synthesis
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
RBFOX3
Metabolic Reprogramming
Fatty acid synthesis-RBFOX3-Acetyl-CoA-α-KG
Target
OGDC
Alternative Names
OGDC; oxoglutarate dehydrogenase complex
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
Online Inquiry