Short Description
Facilitate Human IgG4 detection with this ready-to-use IHC solution, streamlining procedures from antigen retrieval through slide preparation.
Description
Serum IgG4 is a subtype of IgG elevated in autoimmune pancreatitis (AIP) and other diseases. It is a marker for IgG4-related disease (IgG4-RD), a systemic immune-mediated fibro-inflammatory condition, particularly involving the pancreas and salivary glands. A serum IgG4 level of 135 mg/mL is a reliable marker for IgG4-RD, and IgG4 positive plasma cell infiltration is common in the disease.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Analytical Method
Immunohistochemistry