P450-Metric™ Cytochrome P450 11B1 (CYP11B1) ELISA Kit

CAT#: ITS-0326-YL18
Product Type: Assay Kit
Species: Rat, Mouse
Brand: P450-Metric™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantifies CYP11B1 using a double-antibody sandwich ELISA.
Brand
P450-Metric™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
This premium double-antibody sandwich ELISA kit is meticulously formulated for the exact quantitative detection of Cytochrome P450 11B1 across specialized research samples. Providing remarkable analytical specificity and minimal background interference, this research-use-only assay assists investigators in evaluating targeted adrenal glucocorticoid biosynthesis. It serves as a vital laboratory tool for predicting drug-induced adrenal toxicities and determining the metabolic fate of endocrine therapeutics in preclinical pharmacokinetics.
Features
This high-precision sandwich ELISA provides robust quantification of CYP11B1, serving as an essential tool for evaluating targeted drug biotransformation and adrenal metabolic liabilities in ADME studies.
Process Relevance
Monitoring CYP11B1 to profile off-target metabolic effects and screen inhibitors altering endocrine function.
Application Stage
Preclinical drug discovery, ADME profiling, and pharmacokinetic research
Applications
Utilize this quantitative sandwich ELISA to reliably measure target proteins in tissue homogenates and relevant biological fluids.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Sample Type
Serum, plasma, tissue homogenates, cell lysates
Research Areas
ADME; Endocrine Pharmacology; Drug Metabolism; Toxicology
Size
48 / 96 tests
Data Output Type
Absorbance (OD)
LOD
Rat: 0.31 ng/mL
Mouse: 0.057 ng/mL
Species
Rat, Mouse
Storage
Upon receipt, please follow the storage recommendations in the USER MANUAL to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. Do not store at elevated temperatures for extended periods.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Cytochrome P450 11B1 is an essential steroid 11-beta-hydroxylase fundamentally required for targeted adrenal glucocorticoid biosynthesis. In ADME profiling, assessing this enzyme allows researchers to accurately evaluate the metabolic fate of endocrine-targeting drugs and screen for potential adrenal toxicities.
For Research Use Only | Not For Clinical Use
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