P450-Metric™ Cytochrome P450 24A1 (CYP24A1) ELISA Kit

CAT#: ITS-0326-YL16
Product Type: Assay Kit
Species: Human
Brand: P450-Metric™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantifies CYP24A1 using a double-antibody sandwich ELISA.
Brand
P450-Metric™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
This highly specific double-antibody sandwich ELISA kit allows for the precise quantitative assessment of Cytochrome P450 24A1 in experimental cell lysates and biological fluids. Demonstrating superior analytical reproducibility, this research-use-only immunoassay empowers researchers to analyze renal catabolic degradation mechanisms thoroughly. It provides fundamental analytical data required for evaluating the metabolic stability of vitamin D analogs and modeling complex renal drug clearance in ADME research.
Features
This advanced sandwich ELISA delivers highly specific CYP24A1 quantification, enabling meticulous in vitro profiling of target-drug catabolism and xenobiotic interference in renal metabolic pathways.
Process Relevance
Quantifying CYP24A1 to calculate clearance rates and pharmacokinetic stability of targeted secosteroid therapies.
Application Stage
Preclinical drug discovery, ADME profiling, and pharmacokinetic research
Applications
Perform quantitative analysis of target expression in cell lysates and relevant biological matrices using this specific immunoassay.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Sample Type
Serum, plasma, tissue homogenates, cell lysates
Research Areas
ADME; Endocrine Pharmacology; Drug Metabolism; Pharmacokinetics
Size
48 / 96 tests
Data Output Type
Absorbance (OD)
LOD
Human: 0.057 ng/mL
Species
Human
Storage
Upon receipt, please follow the storage recommendations in the USER MANUAL to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. Do not store at elevated temperatures for extended periods.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Cytochrome P450 24A1 governs the catabolic degradation and renal clearance of active vitamin D compounds. Researchers focus on this target to thoroughly evaluate the metabolic stability of therapeutic vitamin D analogs and model complex renal drug elimination mechanisms.
For Research Use Only | Not For Clinical Use
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