MetaVital™ Mouse Dimethylaniline monooxygenase [N-oxide-forming] 2 (FMO2) ELISA Kit

CAT#: ITS-0326-WB18
Product Type: ELISA Kit
Species: Mouse
Target: Mouse Flavin Containing Monooxygenase 2 (FMO2) enzyme
Brand: MetaVital™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantitatively measures FMO2 concentrations in mouse tissues, serum, and cell lysates using sensitive ELISA detection.
Brand
MetaVital™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
MetaVital™ Mouse FMO2 ELISA Kit provides an accurate, high-sensitivity solution for quantifying Flavin Containing Monooxygenase 2 in mouse biological samples. This tool supports preclinical studies on xenobiotic metabolism, drug biotransformation, and tissue-specific enzyme expression with reliable reproducibility.
Features
Highly specific ELISA for mouse FMO2, ensuring precise measurement across tissue, serum, and cellular lysate samples.
Sensitive detection range from 0.156-10 ng/mL enables accurate quantification in low- and mid-level samples.
Lyophilized standards included for stable, reproducible results with consistent inter-assay performance.
Streamlined 96-well format allows efficient processing of multiple samples with minimal technical variability.
Process Relevance
Facilitates precise monitoring of FMO2 to assess xenobiotic metabolism, tissue-specific expression, and enzymatic regulation in mouse models.
Application Stage
Applicable for preclinical pharmacology, toxicology studies, and in vitro metabolic research in mouse systems.
Applications
Quantitative ELISA measurement of FMO2 in mouse tissue homogenates, serum, or cell lysates for pharmacokinetic, toxicological, ADME profiling studies, and metabolic research applications.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Target
Mouse Flavin Containing Monooxygenase 2 (FMO2) enzyme
Detection Method
Colorimetric
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Assay Measures
Quantitative
Research Areas
Drug metabolism, xenobiotic detoxification, pharmacokinetics (ADME), preclinical toxicology, hepatic enzyme regulation, etc.
Size
96 tests
Data Output Type
Quantitative FMO2 concentration measurement using colorimetric ELISA (endpoint).
Assay Range
0.156 ng/ml - 10 ng/ml
Species
Mouse
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
FMO2 is a liver-predominant flavin-containing monooxygenase involved in oxidative metabolism of drugs and xenobiotics. Its activity modulates pharmacokinetics, metabolic clearance, and tissue-specific detoxification processes in preclinical mouse models.
Pathways
FMO2 catalyzes the N-oxidation of nucleophilic xenobiotics and endogenous amines. It functions downstream of substrate uptake and contributes to phase I drug metabolism, interfacing with phase II conjugation pathways.
For Research Use Only | Not For Clinical Use
Online Inquiry