Short Description
This product is a Phosphoglucomutase-targeted RNA modification and metabolomics analysis tool based on the m5C (TRMT61B-YTHDF1/2/3-ALKBH1-FDH-spacer C18) modification and Glycolysis-mediated (NUDT21-Lactyl-CoA-ADP) metabolic analysis system.
Oligonucleotide
2'-OMe, 2'dT (LNP)
RNA Construction
mRNAs-m5C-TRMT61B-YTHDF1/2/3-ALKBH1-FDH-spacer C18
Epigenetic regulator
G9A overexpression
Metabolic alteration
Upregulating serine-glycine biosyntheticpathway
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
NUDT21
Metabolic Reprogramming
Glycolysis-NUDT21-Lactyl-CoA-ADP