Post-translational Modification

PTM refers to the covalent and enzymatic modification of proteins during or after protein biosynthesis, which can affect the structure, stability, function, interaction of the interacting partners and intracellular localization of the protein. PTM is the basis for the treatment of complex cellular processes such as cell division, growth, differentiation, signaling and regulation. In addition, PTM is involved in many cellular processes, including the maintaining of protein structure and integrity, regulation of metabolism and defense processes, cell recognition and morphological changes.

Therefore, analysis of post-translational modifications of proteins, including modification categories and sites, is particularly important for the study of cell biology and disease diagnosis and prevention. At Creative Biolabs, we offer a variety of off-the-shelf PTM services to assist in your scientific research.

Overview of Our PTM Analysis

  • ■ Phosphorylation
  • ■ Glycosylation
  • ■ Methylation
  • ■ Acetylation Analysis
  • ■ Ubiquitination Analysis
  • ■ Nitrosylation Analysis
  • ■ Di-Sulfide Bond Localization
  • ■ SUMOylation
  • ■ Cysteine Modifications
  • ■ Lysine Modifications & Arginine Modifications
  • ■ Methionine Modifications
  • ■ Isomerization
  • ■ Glycation
  • ■ Oxidation
  • ■ Thioether link
  • ■ Lipidation

Overview of Our Testing Techniques

  • √ Peptide mapping with mass spectrometry
  • √ ExactiveTM MS/MS
  • √ Boronate HPLC
  • √ Reversed phase HPLC
  • √ Gel electrophoresis

Feel free to contact us for project quotations and more detailed information.

For Research Use Only | Not For Clinical Use

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