Targeted Monitoring of Gut Microbiota

Creative Biolabs provides a comprehensive services to monitor gut microbiota.

Background

Gut microbiota is a complex group of microorganisms that dwell in the gastrointestinal tract in a mutualistic fashion with hosts. The microbiota offers many benefits to the host, through a range of physiological functions and is increasingly recognized as a mediator of gastrointestinal (GI), immunologic, and neuropsychologic responses to various environmental and physiologic stressors. Dysbiosis, which has been demonstrated to provoke compositional changes of gut microbiota, has been proved to contribute to many diseases including inflammatory bowel diseases, colorectal cancer (CRC), diabetes, neurodegenerative diseases such as Parkinson's disease (PD) and Alzheimer's disease (AD).

Monitoring gut microbiota enables the prediction of disease states and developing therapies to correct dysbiosis. Recent advances in next-generation sequencing and advanced molecular biology approaches have allowed researchers to identify gut microbiota signatures associated with disease processes and, in some cases, establish causality and elucidate underlying mechanisms.

Tools for analyses of the human gut microbiome. Fig.1 Tools for analyses of the human gut microbiome. (Durack, 2019)

One-stop Services

To better understand how exactly the gut microbiome is linked to health or disease status, Creative Biolabs provides a full range of services to monitor gut microbiota for your research needs.

Creative Biolabs has the equipment and experience that are required to perform microbiome research for the human gut and other applications. Our scientists are creating new solutions to help you isolate, culture and identify microbes for the characterization of microbial communities.

We provide gut pathogen identification services using multiple methods including NGS platforms, microarrays and sequencing of large clone libraries. Our scientific team equipped with microbiome and bioinformatics expertise can provide high-quality data to help you advance your microbiome project.

Creative Biolabs provides professional microbial genome editing services which can efficiently and specifically target certain bacterial strains. Our one-stop services include CRISPR design, testing and production services, to precisely remove or cut and replace specific genetic code sequences in bacteria.

We provide comprehensive host responses monitoring solutions via multi-omics methods including metagenomics, metaproteomics and metabolomics.

High Features

Creative Biolabs provides customized services to meet your scientific needs and better accomplish your goals. We support you through the full process, from design, through sample collection, data generation and processing, to the final analysis. Please feel free to contact us for more information.

Reference

  1. Durack, J.; Lynch, S.V. The gut microbiome: relationships with disease and opportunities for therapy. Journal of experimental medicine. 2019, 216(1): 20-40.

For Research Use Only | Not For Clinical Use

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