AccuMetab™ Canine CYP1B1 Enzyme, Catalytically Active
CAT#: ITS-0426-YL41
Product Type: Recombinant Phase I Metabolizing Enzyme
Brand: AccuMetab
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Canine CYP1B1 for reliable preclinical Phase I ADME profiling.
Brand
AccuMetab
Development Stage
ADME
ADME Research Domain
Metabolism
Background
Canine CYP1B1 is utilized to investigate extrahepatic metabolism and localized procarcinogen activation in preclinical dog models. Profiling this enzyme supports translational toxicology and the safety evaluation of environmental or oncology compounds prior to clinical progression.
Key Features
Extrahepatic canine toxicology model; Translates localized tissue toxicity data; Essential for veterinary oncology screening; Supplied in controlled, low-reductase formats
Applications
Drug Metabolism Studies, Preclinical Species Comparison
Research Areas
ADME; Veterinary Pharmacology
Species
Beagle
Expression System
Recombinant enzymes prepared from E. coli and co-expressed with NADPH CYP-reductase.
Physical Form
Liquid
Size
1 nmol
Storage
-80°C
Storage Comment
When stored at -80°C, our product remains stable and retains full functional activity for up to 10 years.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.