MetaVital™ Human Glutathione S Transferase Theta 2 (GSTt2) ELISA Kit

CAT#: ITS-0326-WB51
Product Type: ELISA Kit
Species: Human
Target: Human Glutathione S Transferase Theta 2 (GSTt2) protein
Brand: MetaVital™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantifies Human GSTt2 levels in tissue, cell lysates, and biological fluids using a sensitive ELISA format.
Brand
MetaVital™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
MetaVital™ Human GSTt2 ELISA Kit provides a robust in vitro platform for accurate quantification of GSTt2 in tissue homogenates, cell lysates, and various biological fluids. Using a sandwich ELISA approach, it delivers high specificity and reproducibility for research in enzymology, hepatology, and tumor immunity.
Features
Highly specific sandwich ELISA format pre-coated with GSTt2 antibodies ensures selective detection with minimal cross-reactivity.
Colorimetric detection using TMB substrate allows sensitive quantification across a 1.56-100 mU/ml dynamic range.
Lyophilized standards and reagents provide long-term stability with less than 5% activity loss under proper storage conditions.
Complete 96-well kit includes all necessary reagents for reliable, high-throughput GSTt2 measurement in diverse sample types.
Process Relevance
Supports precise monitoring of GSTt2 levels for enzymatic activity and oxidative stress studies in research workflows.
Application Stage
Suitable for drug discovery, biomarker validation, and mechanistic research in cellular and tissue systems.
Applications
Applicable for quantitative ELISA of GSTt2 in tissue homogenates, cell lysates, serum, plasma, and other biological fluids, supporting ADME profiling studies.
Target
Human Glutathione S Transferase Theta 2 (GSTt2) protein
Detection Method
Colorimetric
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Assay Measures
Quantitative
Research Areas
Enzymology, pharmacokinetics (ADME), tumor immunology, hepatology, cancer research, oxidative stress biology, etc.
Size
96 tests
Data Output Type
Quantitative measurement of GSTt2 enzyme concentration via colorimetric optical density readout.
Assay Range
1.56 mU/ml - 100 mU/ml
LOD
0.94 mU/ml
Species
Human
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Glutathione S Transferase Theta 2 (GSTt2) is a phase II detoxification enzyme critical for conjugating glutathione to electrophilic compounds, protecting cells from oxidative damage. Its dysregulation is associated with liver dysfunction and tumor progression, making it a vital biomarker in biomedical research.
Pathways
GSTt2 participates in cellular detoxification pathways, metabolizing xenobiotics and endogenous toxins. Upstream modulators include oxidative stress signals, while downstream effects influence apoptosis, carcinogen clearance, and antioxidant defense.
For Research Use Only | Not For Clinical Use
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