MetaVital™ Mouse Glutathione S Transferase Theta 2 (GSTt2) ELISA Kit

CAT#: ITS-0326-WB52
Product Type: ELISA Kit
Species: Mouse
Target: Mouse Glutathione S Transferase Theta 2 (GSTt2) enzyme
Brand: MetaVital™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantitatively measures GSTt2 protein levels in mouse tissues, cell lysates, and biological fluids.
Brand
MetaVital™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
MetaVital™ Mouse GSTt2 ELISA Kit enables accurate in vitro quantification of Glutathione S Transferase Theta 2 concentrations in mouse tissue homogenates, cell lysates, and biological fluids, supporting high-throughput research applications.
Features
Sandwich ELISA format with high sensitivity, detecting GSTt2 concentrations as low as 0.94 mU/mL for reliable quantification.
Lyophilized standards and reagents ensure long-term stability, reproducibility, and convenient storage at 4°C upon receipt.
Compatible with tissue homogenates, cell lysates, and various biological fluids, providing broad sample applicability for diverse research studies.
Colorimetric detection using TMB substrate enables precise, reproducible quantification of GSTt2 enzymatic activity in a 96-well plate format.
Process Relevance
Supports quantitative assessment of GSTt2 levels to evaluate enzyme function and oxidative stress responses in mouse models.
Application Stage
Applicable in drug discovery, mechanistic studies, and preclinical biomarker analysis.
Applications
Ideal for ELISA-based quantification in tissue homogenates, cell lysates, and biological fluids, supporting enzymatic activity assessment, ADME profiling studies, and comparative expression analysis.
Target
Mouse Glutathione S Transferase Theta 2 (GSTt2) enzyme
Detection Method
Colorimetric
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Assay Measures
Quantitative
Research Areas
Enzymology, pharmacokinetics (ADME), tumor immunology, hepatology, cancer research, oxidative stress, preclinical pharmacology, etc.
Size
96 tests
Data Output Type
Quantitative protein concentration measurement using sandwich ELISA and colorimetric readout.
Assay Range
1.56 mU/ml - 100 mU/ml
LOD
0.94 mU/ml
Species
Mouse
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
GSTt2 is a phase II detoxification enzyme that conjugates glutathione to reactive electrophiles, mitigating oxidative stress and chemical-induced toxicity. It plays a key role in cellular defense, particularly in liver and immune-related tissues.
Pathways
GSTt2 participates in xenobiotic metabolism and glutathione conjugation pathways, influencing detoxification, reactive oxygen species regulation, and downstream cellular stress responses. Its activity integrates with phase I metabolism and antioxidant defense networks.
For Research Use Only | Not For Clinical Use
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