AccuMetab™ Human CYP1B1 Enzyme, Catalytically Active

CAT#: ITS-0426-YL24
Product Type: Recombinant Phase I Metabolizing Enzyme
Brand: AccuMetab
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Human CYP1B1 for accurate Phase I drug metabolism profiling.
Brand
AccuMetab
Development Stage
ADME
ADME Research Domain
Metabolism
Background
CYP1B1 is an extrahepatic Phase I enzyme that is notably overexpressed in various human malignancies while remaining virtually undetectable in normal tissues. It is widely exploited in oncology ADME studies to evaluate targeted prodrug activation and assess the metabolic mechanisms of hormone-driven cancers.
Key Features
Extrahepatic Phase I oncology target; Validated for tumor-specific prodrug activation; Crucial for hormone-driven cancer research; Supplied in controlled, low-reductase formats
Applications
Drug Metabolism Studies, Reaction Phenotyping, DDI Assessment, Metabolite ID
Research Areas
ADME; Oncology
Species
Human
Expression System
Recombinant enzymes prepared from E. coli and co-expressed with NADPH CYP-reductase.
Physical Form
Liquid
Size
0.5 nmol; 1 nmol; 4 nmol; 10 mg
Storage
-80°C
Storage Comment
When stored at -80°C, our product remains stable and retains full functional activity for up to 10 years.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Our enzyme products are shipped at -80°C.
For Research Use Only | Not For Clinical Use
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