Short Description
Measures cell viablity using a colorimetric method.
Development Stage
Research-Grade Cell-Based Assay Development
Description
This CelluTest™ Cytotoxicity Assay Kit provides a rapid bioluminescent method for evaluating cell membrane integrity in diverse culture systems. The assay quantifies the release of adenylate kinase from damaged cells into the supernatant, utilizing a luciferase-based reaction to produce a light signal. This highly sensitive tool is indispensable for researchers studying cell death mechanisms and evaluating the biological impact of compounds in high-throughput screening protocols.
Features
Employs a non-destructive enzymatic detection method to provide accurate assessments of cell viablity and membrane integrity for high-throughput pharmacological and toxicological screening.
Process Relevance
Evaluating compound toxicity to optimize drug candidate selection and assess cellular robustness.
Application Stage
Drug toxicity testing and cell viablity screening.
Applications
Evaluate compound-induced cell death and membrane integrity in high-throughput screens using cultured primary and immortalized cell lines.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Luminescence
Sample Type
Cell culture supernatants, cell lysates.
Research Areas
Toxicology; Drug Discovery; Oncology
Datasheet