ConjugateIQ™ UDP-Glucuronosyltransferase 1A7 (UGT1A7) ELISA Kit

CAT#: ITS-0326-YL33
Product Type: Assay Kit
Species: Rat
Brand: ConjugateIQ™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantifies UGT1A7 protein using a sandwich ELISA method.
Brand
ConjugateIQ™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
This high-performance sandwich ELISA kit allows for the specific measurement of UGT1A7 protein levels in various extrahepatic tissue models. By enabling precise quantification, the assay supports deep investigations into site-specific drug glucuronidation and detoxification potential. Researchers rely on this tool to evaluate the metabolic profile of diverse substrates, contributing to a better understanding of how localized phase II enzymes influence overall drug disposition and clearance.
Features
Sensitive, reproducible sandwich ELISA designed for accurate UGT1A7 assessment, facilitating studies on extrahepatic drug glucuronidation and detoxification efficiency.
Process Relevance
Characterizing UGT1A7 abundance to optimize extrahepatic drug glucuronidation study protocols and ensure assay consistency.
Application Stage
Drug discovery, preclinical ADME, and metabolic screening.
Applications
Analyze UGT1A7 enzyme levels in extrahepatic tissue models to evaluate site-specific drug glucuronidation and detoxification potential.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Sample Type
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Research Areas
ADME; Drug Metabolism
Size
96 tests
Data Output Type
Absorbance (OD)
LOD
Rat: 0.049 ng/mL
Species
Rat
Storage
Upon receipt, please follow the storage recommendations in the USER MANUAL to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. Do not store at elevated temperatures for extended periods.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
This enzyme is localized primarily in the gastrointestinal tract, where it influences the bioavailability of drugs following oral administration. By catalyzing glucuronidation in the gut, it limits the amount of parent drug reaching the liver.
For Research Use Only | Not For Clinical Use
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