ConjugateIQ™ UDP-Glucuronosyltransferase 2B1 (UGT2B1) ELISA Kit

CAT#: ITS-0326-YL35
Product Type: Assay Kit
Species: Rat
Brand: ConjugateIQ™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantifies UGT2B1 protein using a sandwich ELISA method.
Brand
ConjugateIQ™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
This specialized sandwich ELISA kit provides an efficient way to quantify UGT2B1 enzyme abundance in rodent liver models. The assay is optimized for high-sensitivity protein detection, allowing researchers to accurately characterize glucuronidation kinetics for specific drug substrates. By providing clear expression data, this tool helps investigators understand the phase II metabolic contributions of this enzyme, facilitating the development of improved models for studying drug-drug interactions.
Features
Reliable sandwich ELISA for UGT2B1 measurement, offering accurate protein quantification to evaluate rodent hepatic glucuronidation kinetics for drug development.
Process Relevance
Measuring hepatic UGT2B1 levels to maintain quality control in rodent model metabolic and interaction studies.
Application Stage
Drug discovery, preclinical ADME, and metabolic screening.
Applications
Quantify UGT2B1 enzyme abundance in rodent liver models to characterize glucuronidation kinetics for specific drug substrates.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Sample Type
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Research Areas
ADME; Drug Metabolism
Size
96 tests
Data Output Type
Absorbance (OD)
LOD
Rat: 0.049 ng/mL
Species
Rat
Storage
Upon receipt, please follow the storage recommendations in the USER MANUAL to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. Do not store at elevated temperatures for extended periods.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
This enzyme demonstrates broad substrate specificity, acting on various drugs, fatty acids, and endogenous signaling molecules. Its expression is critical for maintaining metabolic homeostasis and managing the clearance of diverse xenobiotic substrates.
For Research Use Only | Not For Clinical Use
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